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mays , root oxalate (Kidd et al., 2001) and citrate (Pieros et al., 2002) exudation are likely involved in Al-tolerance
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Timing: why fasted, and why evening GH secretagogues and GHRH analogs are studied on an empty stomach for a specific reason: dietary fat and the insulin/glucose rise that follows a meal blunt the GH pulse
However, due to the controlled energy and macronutrient intake, as well as the potential long-term adverse effects, the ketogenic diet should be used for limited periods, possibly cycled, under the strict supervision of a nutritionist