We chose this pharmacologic inhibition as lomustine is already currently used to treat patients with oncologic conditions, including brain tumors and hematologic malignancies (23, 24), and thus this medication would be readily available for any future potential clinical trials on glutathione reductase inhibition in human patients
J Cereb Blood Flow Metab 17:483490 Noda M, Nakanishi H, Akaike N (1999) Glutamate release from microglia via glutamate transporter is enhanced by amyloid-beta peptide
Above all, glutathione is commonly used to improve the detoxification process of the liver
Kovtunovych G, Ghosh MC, Ollivierre W, Weitzel RP, Eckhaus MA, Tisdale JF, et al
The role of increased intestinal permeability in disease progression was reinforced when reduced levels of T1D development were recorded in rodent models fed gluten-free diets (Visser et al
Bridging size and charge effects of mesoporous silica nanoparticles for crossing the bloodbrain barrier
