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The aggregation propensity of huntingtin fibers contributes to the progressive degeneration of cortical and striatal neurons, alongside the formation of neuronal inclusions containing aggregated huntingtin

The sterilized seeds were stratified by dark incubation at 4C for 3 days

Future research with a larger number of patients, can provide new insights regarding the molecular mechanisms as well as modifiable factors to decrease OS in this clinical entity

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