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1,4 Hyperglycemia, dyslipidemia, and insulin resistance activate various metabolic pathways, resulting in oxidative stress, mitochondrial dysfunction, inflammation, and microvascular damage, culminating in neuronal injury, Schwann cell damage, and myelin sheath degeneration

Studies in women with hypoactive sexual desire disorder reported increased subjective arousal and genital engorgement at doses of 0.751.5mg

It helps neutralize free radicals, supports liver detoxification, andmost importantly for skincareinterferes with melanin production, leading to a brighter and more even-toned complexion over time

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However, the weight loss induced by GLP-1R mono-therapies in obese T2DM patients is modest indicating a need for more robust therapeutic options