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Nachtigall MJ, Jessel RH, Flaumenhaft R, et al

Because GLP-1 receptor activation is known to alter gut motility and gastric emptying, changes in bowel habits including both diarrhoea and constipation have been reported in early clinical trials

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[DOI] [PubMed] [Google Scholar] 168.Akinci B., Meral R., Rus D., et al

In contrast, semaglutide works through a different mechanism that does not affect urinary glucose excretion