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may cause iron-deficiency anemia Nausea and vomiting particularly with stricturing disease/obstruction Urgency and tenesmus with rectal/colonic involvement Weight loss and malnutrition due to malabsorption, food avoidance, elevated metabolic demand Fever with active inflammation, abscess, or fistula Perianal disease fissures, fistulae, skin tags, abscesses Extraintestinal Manifestations Arthropathy peripheral or axial (enteropathic arthritis, M07.6x) Dermatologic: Erythema nodosum (L52), pyoderma gangrenosum, psoriasis (L40.5) Ocular: Uveitis/iritis (H20.01), episcleritis, scleritis Hepatobiliary: Primary sclerosing cholangitis (K73.2), fatty liver, cholelithiasis Metabolic: Osteopenia/osteoporosis (from steroid use and malabsorption), nephrolithiasis Hematologic: Anemia (iron deficiency, B12/folate deficiency, anemia of chronic disease) When a patient with Crohns disease is admitted with significant weight loss, malnutrition, or protein-calorie deficiency , query the provider to specify the degree of malnutrition (mild, moderate, severe protein-calorie malnutrition)

Changing priorities in vaccinology: antibiotic resistance moving to the top
BPC-157 vs TB-500 Key Differences in Research BPC-157 and TB-500 are two of the most widely studied peptides in laboratory research involving tissue repair, cellular signalling, and regenerative processes
Glutathione peroxidase 1 (GPX1) is one of the most abundant members of the GPXs family that protects cell from oxidative damage and maintains the balance of intracellular redox systems ( Ebselen [2-phenyl-1,2-benzoisoselenazol-3(2H)-one] is a synthetic organoselenium radical scavenger compound that has GPX-like activity, and it can directly increase GPX1 activity to mimic the effect of GPX1 overproduction
Researchers are encouraged to review primary literature prior to experimental design