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A crossover study of smokers showed that the use of IQOS, e-cigarettes, or CS was associated with acute oxidative stress, platelet function, flow-mediated dilation, and blood pressure, with CS being the most detrimental among the three products 105

Source: The Health Consequences of Smoking50 Years of Progress: A Report of the Surgeon General

and Canada, and 17 per cent of women in the U.K., still smoke during pregnancy.

PMID 31733973