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It is also worth noting that, in clinical practice, histamine intolerance and MCAS are frequently seen alongside other connective tissue conditions, including hypermobile Ehlers-Danlos syndrome (hEDS) and Postural Orthostatic Tachycardia Syndrome (POTS) a triad that overlaps significantly with lipoedema and warrants consideration in women presenting with complex, multisystem symptoms

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That's physiology, not protocol failure

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Confirmation through blood tests Laboratory evidence supports these population-level trends

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