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It plays a crucial role in promoting the growth and maintenance of healthy skin and tissues

Exosomes derived from CAFs in PDAC do not exhibit gemcitabine resistance, however, CAFs promote chemotherapy resistance in PDAC cells by secreting exosomes and maintaining signal exchange with PDAC cells after gemcitabine treatment

Further research in both areas is ongoing

No side effects were reported by the participants in Evans' and Fuller's trial (2016[11])

ROS binds to phospholipids and proteins in cell membranes, leading to protein denaturation and aging pigment or lipofuscin

Cells 2023;12, doi:10.3390/cells12060915