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Therefore, the long non-coding RNA (lncRNA) DUXAP8, by acting on the SLC7A11-mediated ferroptosis pathway, may achieve higher anti-hepatoma efficacy when used in combination with sorafenib[173]

In a phase 2a study (NCT04944992) comparing efinopegdutide with semaglutide in patients with NAFLD, weekly administration of efinopegdutide (10 mg for 24 weeks) achieved a 72.7% reduction in liver fat content vs

doi:10.1086/596476

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