Tributyrin is a triglyceride (fat) form of butyric acid, which the company and published material suggest may be more targeted in delivery than sodium butyrate - a more common but odorous and potentially less colon-specific butyrate supplement form
Excessive alcohol intake suppresses natural killer (NK) cell activity, reduces T and B cell populations, disrupts antigen presentation via the major histocompatibility complex class I (MHC-I) pathway, and diminishes production of antiviral cytokines, including interferons (IFN-/ and IFN-)
doi: 10.1038/s41586-020-2124-0 59 KanekoK
Triggers of IL-1 production have been observed in a number of different stimuli, such as sulfur mustard, nickel, contact allergens or superantigens 36 IL-1 stimulates further release of secondary mediators, including IL-8
[ref][ref] In a study of people with West Nile in Houston, TX, about 20% of the symptomatic people in the study still had continuing fatigue up to 8 years later
This often includes athletes with sports-related injuries like muscle tears or tendonitis, people recovering from surgery, or those with soft tissue damage