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Animal studies have revealed embryofetal toxicity at supratherapeutic doses

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This HCV sequencing information will also be useful for other manufacturers of core-based genotyping assays

With these points in mind, we undertook a broad assessment of published clinical data, curating the body weight loss (% from baseline), glycosylated hemoglobin levels (HbA1c), and nausea responses (% patients reporting) from the SUSTAIN 3, SUSTAIN 7, SCALE Diabetes, SURPASS 2, and STEP 2 trials (17, 22, 64, 66, 67) ( Figures 1AC )

When blood glucose levels are elevated, the kidneys attempt to filter out excess sugar, which draws water with it and results in increased urine output and frequency