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Patients were carefully matched by age, sex, and health status to ensure a fair comparison

12 In the systematic review and meta-analysis from Gibson et al

I do worry about teenagers now

The medication does not increase basal metabolic rate in the traditional sense, but it does improve metabolic efficiency, insulin sensitivity, and fat oxidation, all of which contribute to better energy utilization over time

However, we do know a few things based on emerging studies and general knowledge about weight loss and low-fat dieting (which is generally recommended while taking GLP-1s)

Staying hydrated, using OTC pain relievers, and tracking your triggers usually helps, but talk to a healthcare provider if headaches are severe, frequent, or don't improve