Science 385, 14041404
TT (transfusion-transmitted) virus was reported in the 1990s to cause acute liver failure in about 27% of patients in whom no other cause could be found
(FDA PCAC briefing document, December 2024) The agencys stated concerns were consistent across substances: immunogenicity risk from peptide impurities, inadequate characterization of active pharmaceutical ingredients, and limited human safety data for the proposed routes of administration
What does have a reasonable evidence base: protein at meals stimulates L-cell GLP-1 release and suppresses ghrelin
Methylation reactions are vital for the production and the recycling of many important proteins, hormones, and neurotransmitters required for everyday bodily functions
One of those companies, LifeVantage, fraudulently said one of its best-selling substances, Protandim, was developed by a biochemist, when it was really cooked up by a business executive