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GLP-1 medications can produce substantial caloric restriction through appetite suppression and early satiety, leading to weight loss that may exceed 15-20% of body weight over several months with higher doses of semaglutide 2.4 mg or tirzepatide
10.1002/jnr.24203 Wiley Interdiscip Rev Membr Transp Signal
This has been confirmed by the observation that Nrf2-deficient mice displayed increased pulmonary inflammation following LPS treatment and that Nrf2 inducers significantly attenuated this effect [59]
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iu kin bo qun Bo qun trong bao b kn, ni kh ro, trnh nh nng, nhit di 30 C