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The suggestion

Its a tricky clue, five across

Capsules and edibles: no inhalation, lower bioavailability (6-15%), onset of action 60-120 minutes, but no lung exposure

JTI is one of the largest tobacco companies globally and notably produces a variety of reduced-risk products, namely e-cigarette brands and heated tobacco products (Ploom)

From rogerebert.com November 5, 1999 Michael Mann's "The Insider" makes a thriller and expose out of how big tobacco's long-running tissue of lies was finally exposed by investigative journalism

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