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The mechanism is understood, the outcomes are predictable, and the safety profile at appropriate concentrations is well characterised

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When supplementing with folate or B12, be sure that it is the methylated version of those vitamins

Dex could reduce the expression of autophagy-related proteins Beclin-1 and microtubule-associated protein 1 light chain 3I/II(LC3I/II) in TBI in rats, attenuating the disruption of the blood-brain barrier, brain edema, and apoptosis [63]

Serious adverse effects require clinical vigilance: Pancreatitis : Patients should be counseled to seek immediate medical attention for severe, persistent abdominal pain radiating to the back, with or without vomiting

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