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[DOI] [PubMed] [Google Scholar] Li Y., Hansotia T., Yusta B., Ris F., Halban P.A., Drucker D.J

The combination of PMC and X-rays activated ferroptosis in MM cells and heterologous plants, delivering evidence for the development of lipid peroxidation, GPX4 inhibition, Fe 2+ release, and GSH reduction

The prepared supernatant was subjected to liquid chromatography-mass spectrometry (LC-MS)/MS

Sources : Pekala J, Patkowska-Sokoa B, Bodkowski R, et al

Nevertheless, factors such as solubility, toxicity, and suboptimal renal targeting must also be carefully addressed [80]

Important safety considerations include a boxed warning for thyroid C-cell tumors, contraindications in patients with personal/family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2, and risks of pancreatitis, gallbladder disease, hypoglycemia (when used with insulin or insulin secretagogues), and acute kidney injury