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It is helpful to distinguish between urinary frequency (passing urine more than 8 times in 24 hours, often in small volumes) and polyuria (producing more than 3 litres of urine per day)

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Modern clinical research has shown that saffron supplementation (typically 2050mg per day) can improve visual acuity, retinal function, and contrast sensitivity in adults with AMD.58 These effects are attributed to compounds called crocin and crocetin, which may enhance retinal blood flow and protect photoreceptor cells from oxidative stress