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One randomized, placebo-controlled trial involving healthy humans found that eating anthocyanins-rich, purple-fleshed potatoes for six weeks reduced the levels of inflammatory markers like IL-6 and C-reactive protein (CRP) and the oxidative DNA-damage marker 8-hydroxydeoxyguanosine (8-HdG) (205)

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This peripheral restriction is fundamentally different from compounds like Semaglutide (a GLP-1 agonist that acts centrally to reduce appetite) or ghrelin-modulating agents that directly influence hunger hormones