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2 The development of these longer acting alternatives has allowed GLP-1 receptor agonists to become a promising therapeutic option for patients with diabetes
Because glucagon was known to stimulate insulin secretion [13], it was natural to look at the newly identified glucagon-like peptides that possessed 50% sequence homology to glucagon
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The domain of G0S2 which inhibits PNPLA2 comprises amino acids K20-A52 and does not inhibit the function of other PNPLA family members PNPLA6 and 7, or HSL, MGL, and lipoprotein lipase (54)
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