This information article is intended to provide general information about skin diseases
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Dong Y, Chi Y, Lin X, Zheng L, Chen L, Chen G
In primary insufficiency there is a decrease in both mineralocorticoids (aldosterone) and glucocorticoids (cortisol), whereas in secondary and tertiary insufficiency the aldosterone levels are virtually normal as the zona glomerulosa is largely independent of ACTH (see webpage on adrenal Function)
Therefore, the protective activity of GSH is two-fold it enhances the activity of immune cells and functions as an antioxidant within them