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Doserelated effects on the rat fetus (structural abnormalities and reduced body weight) occurred only at higher dosages, equal to or greater than 150 mg/kg (more than 2344-times the 10 mg clinical dose, based on AUC), which were associated with maternal toxicity
ROS are known to activate several Ca-permeable channels in the plasma membrane, facilitating increased calcium influx into cells [40]
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Goldenrod contributes diuretic, anti-inflammatory, and antimicrobial properties that support healthy urine flow and reduce urinary tract irritation
RNAse A was added, and samples were incubated at 37 C for 30 min
I can't say anything about the long-term effect yet
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