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For patients with severe obesity (BMI 40 kg/m or 35 kg/m with comorbidities) who have not achieved adequate weight loss with lifestyle and pharmacological interventions, bariatric surgery may be considered

Eli Lilly, the pharmaceutical company behind retatrutide, declined to comment on the protocols of its ongoing trials but stated that patient safety is a priority

Association of nonalcoholic fatty liver disease with subclinical cardiovascular changes: a systematic review and meta-analysis

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Insulin resistance is associated with metabolic dysfunction-associated steatotic liver disease (MASLD, formerly known as NAFLD), polycystic ovary syndrome (PCOS), obstructive sleep apnea, and certain metabolic-related conditions