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Human data semaglutide/tirzepatide: extensive, approved for type 2 diabetes and obesity

Peptide solutions should also be handled carefully using sterile techniques to help prevent contamination

Used needles and syringes should be placed in an FDA-cleared puncture-proof sharps container rather than household trash to prevent needle-stick injuries

Wang M, Zhang X, Zhao H, Wang Q, Pan Y

Notably, no cases of clinically significant hypoglycemia, medullary thyroid cancer, or C-cell hyperplasia were reported in published trial data

This off-label combination has not been studied in clinical trials and could produce additive GI side effects similar to or exceeding those seen with CagriSema