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While the classical InsR-B is primarily involved in control of glucose uptake and metabolism [25], InsR-A (normally expressed in fetal tissues) promotes mitosis, cell invasion and protection from apoptosis upon IGF-2 stimulation in a variety of cancers [26,27,28,29,30,31,32]

Cai, C., et al., Empagliflozin attenuates cardiac microvascular ischemia/reperfusion through activating the AMPK1/ULK1/FUNDC1/mitophagy pathway

Lymphocytes treated with Livagen show increased transcriptional activity, particularly in genes involved in immune function that had become silenced with age

The peptide mimetic compounds, vilda-, saxa, and teneligliptin, were identified by replacement experiments of peptide-based substrates, whereas the non-peptide mimetic compounds, sita, alo-, and linagliptin, were derived from initially found inhibitors of random screenings

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